Cryospraying by near-critical carbon dioxide: solid microparticles with improved biopharmaceutical properties

Variosol ® is an innovative particle technology, based on the use of near-critical carbon dioxide. When expanding from near-critical conditions, CO2 has favourable physical properties as a spraying agent and refrigerant, and it can be used as an atomizing and crystallizing medium, generating microparticles with narrow size distribution and improved biopharmaceutical properties.

Variosol ® cryospraying technology can address many technical and economical challenges faced today by pharmaceutical industry. It offers significant advantages over existing micronization methods and over supecritical fluid based processes.

The Nautilus shell spiral is considered a symbol of beauty and proportional perfection in Nature, since ancient Greece times. Its perfect logarithmic spiral arises from the need to maintain the same proportions throughout growth, while ensuring structural strength and lightness to the shell.
SiTec PharmaBio has made this shell spiral its symbol to emphasize its commitment to create and maintain high professional standards and value to the pharmaceutical business, offering strong expertise and a lean, effectively built structure.